The William Blake Collection consists of more than 200 titles of which the majority are facsimiles of Blake's works or privately-printed reprints and editions containing facsimiles of the illustrations. The collection also forms part of a larger collection devoted to joint painter-illustrator-author books that include followers of Blake, e.g. Palmer & Calvert, William Morris, Eric Gill, and David Jones.

One of the highlights of the William Blake Collection is the 1951 Trianon Press edition of William Blake's Jerusalem.

A collection of seven zines created by Jenna Rose Sands on topics including cultural appropriation, residential schools, missing and murdered Indigenous women and girls, Pow Wow etiquette and the 60s scoop. Much of the artwork is hand-drawn and includes collage work.